By Victor Kanayo
Manchester United will visit Tottenham Hotspur in the Carabao Cup quarter-finals.
Holders Liverpool will visit Premier League strugglers Southampton.
Arsenal host Crystal Palace in a London derby, while Newcastle United are at home to Brentford.
The quarter-final ties will take place in the week of December 16, 2024.
It is the first time in 14 years there have been no EFL clubs in the League Cup quarter-final.
Spurs beat Manchester City in the fourth round, while United – who beat Leicester 5-2 under interim boss Ruud van Nistelrooy – will hope to have Ruben Amorim in charge by then.
The semi-finals will be played across two legs in the week of 6 January and 3 February, with the final at Wembley Stadium on Sunday, 16 March.